Are Covid Vaccines That Defend Against Omicron Variants Too Late?
Are Covid Vaccines That Defend Against Omicron Variants Too Late?
The discovery of the long-term effects of long-term flu vaccination appears in a new paper, by researchers at the US Army’s National Institute of Allergy and Infectious Diseases.
Vaccinations that are lifelong can reduce negative response to all three viruses, including flu and influenza, the paper says. But if they are followed at a later time, the vaccine-preventable response may be more severe.
“The risk of uncontrolled or delayed influenza vaccination is very low compared with other vaccines that are easily administered anywhere in the world,” says Daniel J. Glees of the University of California San Francisco.
The vaccine needs to be administered at the doses that can be given for long periods, says Glees, who is not involved in the study.
The vaccines have been shown to prevent devastating cold, flu, and other diseases, as well as cancer and genetic diseases. However, researchers have highlighted concerns that they could be too small to prevent all four common colds.
The report also found that people taking the vaccines should be screened by their healthcare provider, since it is increasingly common for people to receive doses that are too high to be more effective.
An active-duty US Army Soldier’s Vaccine for All Ordinary People is at UL’s School of Medicine Immunization Training at Fort Carson, Arizona. (YouTube)
The paper does not explain why the vaccine is less effective than one which is given a shorter interval. But it suggests that a longer interval may be helpful, as influenza vaccines may work better at preventing the disease than otherwise.
“[The longer] interval is related to protective regimens, such as rest and relaxation, so this is a good standard for evaluating the effectiveness of influenza vaccines,” says Katherine O’Rourke, an associate professor of infectious diseases and infectious disease at Washington University in St. Louis.
To test whether these vaccines are safe enough to be given at a late or early age, scientists tested 250 kids aged 5 to 14 years, administering doses ranging from 1.5 to 6.5 doses a day to “double the duration of up to four days in children on the active duty health care register.”
The vaccine contains PKB-2 inhibitors, which are more potent than flu vaccines, but the group didn’t use them to reduce the chances that they would develop influenza at that age, the study said.
The children who came up with the same vaccine had the same one-year risk of influenza compared with that in the control group, but the two groups don’t mix, the study notes.
The researchers speculate that the vaccine may interfere with the immune system’s ability to fight off infections, which might include influenza.
“At the end of a long-term, healthy and well-maintained life, an influenza vaccine should be a win-win for health care professionals and patients,” the researchers write.
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